Teriflunomide impurity 3

CAS No. 1011244-72-6

Teriflunomide impurity 3 ( 4-Amino-N-(4-trifluoromethylphenyl)benzamide )

Catalog No. M23218 CAS No. 1011244-72-6

Teriflunomide impurity 3 is a selective COX-1 inhibitor(IC50 of 30 μM). It is less active against COX-2 (IC50>100 μM).

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 35 In Stock
10MG 65 In Stock
25MG 125 In Stock
50MG 205 In Stock
100MG 335 In Stock
200MG 478 In Stock
500MG 772 In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    Teriflunomide impurity 3
  • Note
    Research use only, not for human use.
  • Brief Description
    Teriflunomide impurity 3 is a selective COX-1 inhibitor(IC50 of 30 μM). It is less active against COX-2 (IC50>100 μM).
  • Description
    Teriflunomide impurity 3 is a selective COX-1 inhibitor(IC50 of 30 μM). It is less active against COX-2 (IC50>100 μM).
  • Synonyms
    4-Amino-N-(4-trifluoromethylphenyl)benzamide
  • Pathway
    Chromatin/Epigenetic
  • Target
    COX
  • Recptor
    COX-1;COX-2
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1011244-72-6
  • Formula Weight
    280.3
  • Molecular Formula
    C14H11F3N2O
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:250 mg/mL (892.06 mM; Need ultrasonic)
  • SMILES
    O=C(NC1=CC=C(C(F)(F)F)C=C1)C2=CC=C(N)C=C2
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Hiroki Kakuta, et al. Cyclooxygenase-1-selective inhibitors are attractive candidates for analgesics that do not cause gastric damage. design and in vitro/in vivo evaluation of a benzamide-type cyclooxygenase-1 selective inhibitor. J Med Chem. 2008 Apr 24;51(8):2400-11.
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